Main objectives of the BKU:
Nowadays, life science and medical researchers face unprecedented computational challenges when trying to understand complex biological systems in depth, discover the cause of disease states, find novel drug targets, etc. The mission of the Technion Bioinformatics Knowledge Unit (BKU) is to empower life sciences researchers at the Technion and its affiliated hospitals by providing bioinformatics advice using up-to-date computational methods and software tools.
- Bioinformatics Support: Provide bioinformatics consulting, make advanced computational methods and tools available to researchers and medical doctors.
- Development: Develop new state of-the-art bioinformatics strategies
- Education: Organize bioinformatics courses and workshops to introduce cutting edge technologies and research, new bioinformatics approaches and tools
Main research topics supported by the BKU:
- Basic and advanced analyses of data derived from high throughput genome sequencing, gene expression, binding assays etc.
- Data integration of omics data such as transcriptome, metabolome, proteome and interactome.
- Structural bioinformatics: structure-based function prediction, macromolecular structure prediction, small molecule docking, pharmacofore prediction, etc.
Members of the Unit:
Dr Michael Shmoish- Genomics/ Transcriptomics Microarrays / R-system
Dr. Fabian Glaser- Structural Biology/Protein Bioinformatics/Docking/Homology modeling/Molecular dynamics/ Phylogenetics/Perl,
Dr. Elizabeth Bartom- Downstream analysis and data integration of high throughput sequencing and other -omics data, RNA-seq and Chip-seq analyses
Dr. Ofir Tal- Structural Bioinformatics/ Docking/homology modeling
Alona Rabner- Protein and RNA Bioinformatics, CLIP-Seq analysis
Unit website: http://bku.technion.ac.il/